BDBM19586 (2S)-N-{2-[(4-methoxy-2,6-dimethylphenyl)amino]ethyl}-4-methyl-2-[(3-methylphenyl)formamido]pentanamide::arylaminoethyl amide, 3b

SMILES COc1cc(C)c(NCCNC(=O)[C@H](CC(C)C)NC(=O)c2cccc(C)c2)c(C)c1

InChI Key InChIKey=RNVBYSSYXDLACM-QFIPXVFZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19586   

TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19586((2S)-N-{2-[(4-methoxy-2,6-dimethylphenyl)amino]eth...)
Affinity DataKi:  14nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19586((2S)-N-{2-[(4-methoxy-2,6-dimethylphenyl)amino]eth...)
Affinity DataKi:  131nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19586((2S)-N-{2-[(4-methoxy-2,6-dimethylphenyl)amino]eth...)
Affinity DataKi:  132nM ΔG°:  -9.76kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed