BDBM19603 (2S)-4-cyclohexyl-N-[(2R,3R)-1-(5-fluoro-2,3-dihydro-1H-indol-1-yl)-3-hydroxybutan-2-yl]-2-[(3-methoxyphenyl)formamido]butanamide::arylaminoethyl amide, 8k

SMILES COc1cccc(c1)C(=O)N[C@@H](CCC1CCCCC1)C(=O)N[C@H](CN1CCc2cc(F)ccc12)[C@@H](C)O

InChI Key InChIKey=WDFFUHXXXVWAOH-JAMKYWPSSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19603   

TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19603((2S)-4-cyclohexyl-N-[(2R,3R)-1-(5-fluoro-2,3-dihyd...)
Affinity DataKi:  8nM ΔG°:  -11.5kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19603((2S)-4-cyclohexyl-N-[(2R,3R)-1-(5-fluoro-2,3-dihyd...)
Affinity DataKi:  20nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19603((2S)-4-cyclohexyl-N-[(2R,3R)-1-(5-fluoro-2,3-dihyd...)
Affinity DataKi:  2.75E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed