BDBM19631 (2S)-2-(1,3-benzoxazol-2-ylamino)-N-[(2R)-1-(benzyloxy)-3-(5-fluoro-2,3-dihydro-1H-indol-1-yl)propan-2-yl]-3-cyclohexylpropanamide::Heterocyclic arylaminoethyl amide, 13c

SMILES Fc1ccc2N(C[C@H](COCc3ccccc3)NC(=O)[C@H](CC3CCCCC3)Nc3nc4ccccc4o3)CCc2c1

InChI Key InChIKey=YYDWMUXZSMHCTN-DGPALRBDSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19631   

TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19631((2S)-2-(1,3-benzoxazol-2-ylamino)-N-[(2R)-1-(benzy...)
Affinity DataKi:  5nM ΔG°:  -11.8kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19631((2S)-2-(1,3-benzoxazol-2-ylamino)-N-[(2R)-1-(benzy...)
Affinity DataKi:  1.49E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19631((2S)-2-(1,3-benzoxazol-2-ylamino)-N-[(2R)-1-(benzy...)
Affinity DataKi:  1.67E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed