BDBM19634 (3S)-3-[(2S)-2-(1,3-benzoxazol-2-ylamino)-3-cyclohexylpropanamido]-4-(5-fluoro-2,3-dihydro-1H-indol-1-yl)butanoic acid::Heterocyclic arylaminoethyl amide, 13f

SMILES OC(=O)C[C@@H](CN1CCc2cc(F)ccc12)NC(=O)[C@H](CC1CCCCC1)Nc1nc2ccccc2o1

InChI Key InChIKey=PLORMMYDFRWDDE-GMAHTHKFSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19634   

TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19634((3S)-3-[(2S)-2-(1,3-benzoxazol-2-ylamino)-3-cycloh...)
Affinity DataKi:  12nM ΔG°:  -11.2kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19634((3S)-3-[(2S)-2-(1,3-benzoxazol-2-ylamino)-3-cycloh...)
Affinity DataKi: >1.00E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19634((3S)-3-[(2S)-2-(1,3-benzoxazol-2-ylamino)-3-cycloh...)
Affinity DataKi: >2.00E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed