BDBM19645 (2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo-N-[(2S)-1-{[4-(trifluoromethoxy)phenyl]amino}pentan-2-yl]butanamide::succinamide peptidomimetic, 11
SMILES CCC[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@H](CC1CCCCC1)CC(=O)N1CCOCC1
InChI Key InChIKey=IHRRAJSHRLAXAQ-GGAORHGYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 19645
Affinity DataKi: 13nM ΔG°: -11.2kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Affinity DataKi: 285nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Affinity DataKi: 557nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair