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BDBM197915 US9216988, 185

SMILES: CC(C)CN(Cc1ccc(cc1)N1CCC2(CCCO2)C1)S(=O)(=O)Cc1ccccc1

InChI Key: InChIKey=ZGCLYZPOQPVYLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197915   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))
BDBM197915
PNG
(US9216988, 185)
Show SMILES CC(C)CN(Cc1ccc(cc1)N1CCC2(CCCO2)C1)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1S/C25H34N2O3S/c1-21(2)17-27(31(28,29)19-23-7-4-3-5-8-23)18-22-9-11-24(12-10-22)26-15-14-25(20-26)13-6-16-30-25/h3-5,7-12,21H,6,13-20H2,1-2H3
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 80n/an/an/an/a7.4n/a



Genentech Inc

US Patent


Assay Description
On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash bu...


US Patent US9216988 (2015)


BindingDB Entry DOI: 10.7270/Q2TB15QC
More data for this
Ligand-Target Pair