BDBM198174 2-((5-(4-Methoxyphenylamino)-1,3,4-thiadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (4c)
SMILES COc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)s2)cc1
InChI Key InChIKey=RUFINCLRAHCHCC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 198174
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)
Indian Institute Of Technology (Banaras Hindu University)
Affinity DataKi: 770nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)
Indian Institute Of Technology (Banaras Hindu University)
Affinity DataIC50: 6.01E+4nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)
Indian Institute Of Technology (Banaras Hindu University)
Affinity DataIC50: 900nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair