BDBM19860 4-[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]-N-{1-[(2,2,2-trifluoroethyl)carbamoyl]cyclohexyl}benzamide::piperazine-containing compound, 2

SMILES CN1CCN(CC1)c1nc(cs1)-c1ccc(cc1)C(=O)NC1(CCCCC1)C(=O)NCC(F)(F)F

InChI Key InChIKey=OPPAJAHIIRKXDZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19860   

TargetCathepsin S(Mus musculus (Mouse))
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19860(4-[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]-N-...)
Affinity DataIC50:  3.30E+4nM EC50: >1.00E+4nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed