BDBM202413 US9238644, 20

SMILES NC(=O)C1(CC1)c1ccccc1CCc1nc(Nc2cnn(c2)C2CCNC2)ncc1Cl

InChI Key InChIKey=UMAZVUGSOHOIKQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 202413   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cancer Therapeutics Crc Pty

US Patent
LigandPNGBDBM202413(US9238644, 20)
Affinity DataIC50:  1.76E+3nMpH: 7.2 T: 2°CAssay Description:Adult human umbilical vein endothelial cells (HUVEC) (Cat# CC-2519, Lonza) were seeded into clear-bottom, TC treated 12 well plates (Cat #665180, G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Cancer Therapeutics Crc Pty

US Patent
LigandPNGBDBM202413(US9238644, 20)
Affinity DataIC50:  38nMpH: 7.2 T: 2°CAssay Description:Adult human dermal lymphatic microvascular endothelial cells (HMVEC-dLyAD) (Cat# CC-2810, Lonza) were seeded into clear-bottom, TC treated 12 well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Cancer Therapeutics Crc Pty

US Patent
LigandPNGBDBM202413(US9238644, 20)
Affinity DataIC50:  7nMpH: 7.4Assay Description:A biotin labelled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent