BDBM202920 US9242970, 67

SMILES COc1cncc(OC)c1C1CCCC(=O)N1Cc1cccc(c1)-n1nccn1

InChI Key InChIKey=AFLPVDYCVMAMQP-UHFFFAOYSA-N

Data  2 IC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 202920   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

US Patent
LigandPNGBDBM202920(US9242970, 67)
Show SMILES COc1cncc(OC)c1C1CCCC(=O)N1Cc1cccc(c1)-n1nccn1
Show InChI InChI=1S/C21H23N5O3/c1-28-18-12-22-13-19(29-2)21(18)17-7-4-8-20(27)25(17)14-15-5-3-6-16(11-15)26-23-9-10-24-26/h3,5-6,9-13,17H,4,7-8,14H2,1-2H3
Affinity DataIC50: 163nMT: 2°CAssay Description:In Vitro Assay: Intracellular Calcium Measurements:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetOrexin receptor type 2(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

US Patent
LigandPNGBDBM202920(US9242970, 67)
Show SMILES COc1cncc(OC)c1C1CCCC(=O)N1Cc1cccc(c1)-n1nccn1
Show InChI InChI=1S/C21H23N5O3/c1-28-18-12-22-13-19(29-2)21(18)17-7-4-8-20(27)25(17)14-15-5-3-6-16(11-15)26-23-9-10-24-26/h3,5-6,9-13,17H,4,7-8,14H2,1-2H3
Affinity DataIC50: 156nMT: 2°CAssay Description:In Vitro Assay: Intracellular Calcium Measurements:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid