BDBM203056 US9242970, 227

SMILES Fc1cccc(c1C1CCCC(=O)N1Cc1ccc(OC(F)(F)F)cc1)C(F)(F)F

InChI Key InChIKey=AKHRIKMRYSIIOK-UHFFFAOYSA-N

Data  2 IC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 203056   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

US Patent
LigandPNGBDBM203056(US9242970, 227)
Show SMILES Fc1cccc(c1C1CCCC(=O)N1Cc1ccc(OC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C20H16F7NO2/c21-15-4-1-3-14(19(22,23)24)18(15)16-5-2-6-17(29)28(16)11-12-7-9-13(10-8-12)30-20(25,26)27/h1,3-4,7-10,16H,2,5-6,11H2
Affinity DataIC50: 3.50E+3nMT: 2°CAssay Description:In Vitro Assay: Intracellular Calcium Measurements:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetOrexin receptor type 2(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

US Patent
LigandPNGBDBM203056(US9242970, 227)
Show SMILES Fc1cccc(c1C1CCCC(=O)N1Cc1ccc(OC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C20H16F7NO2/c21-15-4-1-3-14(19(22,23)24)18(15)16-5-2-6-17(29)28(16)11-12-7-9-13(10-8-12)30-20(25,26)27/h1,3-4,7-10,16H,2,5-6,11H2
Affinity DataIC50: 5.90E+3nMT: 2°CAssay Description:In Vitro Assay: Intracellular Calcium Measurements:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid