BDBM204117 US9539260, I2::US9763952, Example I2

SMILES COc1ncc(cc1C(F)F)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)C3CCS(=O)(=O)CC3)c(F)c12

InChI Key InChIKey=ZMAYVCWSSMGOSU-KRWDZBQOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 204117   

LigandPNGBDBM204117(US9539260, I2 | US9763952, Example I2)
Affinity DataIC50:  308nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM204117(US9539260, I2 | US9763952, Example I2)
Affinity DataIC50:  5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM204117(US9539260, I2 | US9763952, Example I2)
Affinity DataIC50:  308nMAssay Description:The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The final concentrations of ATP and p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM204117(US9539260, I2 | US9763952, Example I2)
Affinity DataIC50:  5nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent