BDBM205464 PPiase inhibitor, 1

SMILES C1CN1c1nc(nc(n1)-c1cccn1-c1ccccc1)N1CC1

InChI Key InChIKey=DAZONCQAIYYVKR-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 205464   

TargetInorganic pyrophosphatase(Mycobacterium tuberculosis)
University Of Kentucky

LigandPNGBDBM205464(PPiase inhibitor, 1)
Affinity DataIC50:  1.30E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
TargetProbable manganese-dependent inorganic pyrophosphatase(Staphylococcus aureus (Firmicutes))
University Of Kentucky

LigandPNGBDBM205464(PPiase inhibitor, 1)
Affinity DataIC50: >6.00E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInorganic pyrophosphatase(Saccharomyces cerevisiae (Yeast))
University Of Kentucky

LigandPNGBDBM205464(PPiase inhibitor, 1)
Affinity DataIC50:  3.55E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInorganic pyrophosphatase(Escherichia coli (Enterobacteria))
University Of Kentucky

LigandPNGBDBM205464(PPiase inhibitor, 1)
Affinity DataIC50:  2.33E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed