BDBM206108 US9255110, 21

SMILES CC(O)CC(C)Oc1cc2ncccc2cc1NC(=O)c1csc2cncnc12

InChI Key InChIKey=HRNAVIYNHGZRMP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 206108   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Roche Palo Alto

US Patent
LigandPNGBDBM206108(US9255110, 21)
Affinity DataIC50:  24nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Roche Palo Alto

US Patent
LigandPNGBDBM206108(US9255110, 21)
Affinity DataIC50:  449nMpH: 7.2 T: 2°CAssay Description:SYK activity is measured by phosphorylation of a peptide substrate (Biotin-EPEGDYEEVLE) with [gamma-33P] ATP. The enzyme reaction was conducted at 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Roche Palo Alto

US Patent
LigandPNGBDBM206108(US9255110, 21)
Affinity DataIC50:  760nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent