BDBM207140 US9260439, 117
SMILES CNS(=O)(=O)N1C[C@@H](OC)[C@@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOC[C@@H]1C
InChI Key InChIKey=IIILFJZWUSDOMV-IAOVAPTHSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 207140
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha [Q431L,Q432E,D433V,Q434L,V435F,V436Q,K437G,E438P]/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
Affinity DataKi: 0.179nMAssay Description:PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
Affinity DataKi: 0.256nMAssay Description:PI3KA_FL: Genes encoding for full length p110alpha and p85alpha subunits of PI3Kalpha complex were subcloned from existing constructs into pFASTBAC D...More data for this Ligand-Target Pair