BDBM20733 4-(6-hydroxy-1,2-benzoxazol-3-yl)benzene-1,3-diol::Benzisoxazole, 14::CHEMBL360410

SMILES Oc1ccc(-c2noc3cc(O)ccc23)c(O)c1

InChI Key InChIKey=NBTXJDAHLMMIGY-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 20733   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM20733(4-(6-hydroxy-1,2-benzoxazol-3-yl)benzene-1,3-diol ...)
Affinity DataIC50:  1.52E+4nMpH: 7.3 T: 2°CAssay Description:Compounds were assayed over a threefold dilution series in a 96-well plate format to determine IC50 values. The reaction was allowed to proceed with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM20733(4-(6-hydroxy-1,2-benzoxazol-3-yl)benzene-1,3-diol ...)
Affinity DataIC50:  24nMAssay Description:Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM20733(4-(6-hydroxy-1,2-benzoxazol-3-yl)benzene-1,3-diol ...)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair