BDBM207584 US10501467, Example 29::US9260440, 29::US9617273, Example 29
SMILES CC1(C)Cc2n(CCN(Cc3ccccc3)Cc3ccccc3)c3cccc4c3c2c(C1)n[nH]c4=O
InChI Key InChIKey=HYWFTJKIAJYAFU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 207584
Affinity DataIC50: >1.00E+3nMpH: 8.0Assay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of human PARP-1 catalytic domain (662 to 1011 residues) expressed in Escherichia coli BL21(DE3) cells pre-incubated for 30 mins before add...More data for this Ligand-Target Pair
Affinity DataEC50: 630nMAssay Description:Inhibition of PARP-1 in human HeLa cells incubated for 18 hrs in presence of H2O2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair