BDBM20772 5-{6-amino-8-[(7-chloro-1,3-benzothiazol-2-yl)sulfanyl]-9H-purin-9-yl}pentanenitrile::Benzothiazole analogue, 25

SMILES Nc1ncnc2n(CCCCC#N)c(Sc3nc4cccc(Cl)c4s3)nc12

InChI Key InChIKey=VDMMKENUYLBUEL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20772   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Conforma Therapeutics

LigandPNGBDBM20772(5-{6-amino-8-[(7-chloro-1,3-benzothiazol-2-yl)sulf...)
Affinity DataEC50:  110nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed