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BDBM207965 US9266848, 3

SMILES: ONC(=O)[C@H](CNC(=O)c1ccc(OCc2cc(Cl)nc(Cl)c2)cc1)N1CCCCC1

InChI Key: InChIKey=JZGAMBBGGHNFGW-KRWDZBQOSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207965   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Disintegrin and metalloproteinase domain-containing protein 17


(Homo sapiens (Human))
BDBM207965
PNG
(US9266848, 3)
Show SMILES ONC(=O)[C@H](CNC(=O)c1ccc(OCc2cc(Cl)nc(Cl)c2)cc1)N1CCCCC1
Show InChI InChI=1S/C21H24Cl2N4O4/c22-18-10-14(11-19(23)25-18)13-31-16-6-4-15(5-7-16)20(28)24-12-17(21(29)26-30)27-8-2-1-3-9-27/h4-7,10-11,17,30H,1-3,8-9,12-13H2,(H,24,28)(H,26,29)/t17-/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 255n/an/an/an/a7.437



Galderma Research & Development

US Patent


Assay Description
The TACE enzyme is an internal production (carried out according to the publication Protein Eng Des Sel, 2006, 19, 155-161) and is added so as to hav...


US Patent US9266848 (2016)


BindingDB Entry DOI: 10.7270/Q2TM78ZS
More data for this
Ligand-Target Pair