BDBM208966 US9266881, A-3
SMILES Cc1ccc(cc1)-c1cccc2nn(CCc3ccc4ccccc4n3)c(=O)n12
InChI Key InChIKey=SCPQSVKZPWUYHV-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 208966
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 17nM ΔG°: -10.6kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAPĀ® FP kit supplied by Molecular Devices, Sunn...More data for this Ligand-Target Pair