BDBM212880 US9278960, 2-27::US9663506, Example 2-27

SMILES CC1CCC(=CC1)c1cc(nc2cc(CN3C(=O)CCC3=O)ccc12)C(N)=O

InChI Key InChIKey=PQQJZVOILCUNMH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 212880   

LigandPNGBDBM212880(US9278960, 2-27 | US9663506, Example 2-27)
Affinity DataIC50:  7nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM212880(US9278960, 2-27 | US9663506, Example 2-27)
Affinity DataIC50:  7nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM212880(US9278960, 2-27 | US9663506, Example 2-27)
Affinity DataIC50:  7nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent