BDBM213002 US9278960, 4-86::US9663506, Example 4-86

SMILES NC(=O)c1cc(-c2cnn(CF)c2)c2ccc(CN3CCO[C@H](C3)C(F)(F)F)cc2n1

InChI Key InChIKey=NYDKXJPCFKVTFU-GOSISDBHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 213002   

LigandPNGBDBM213002(US9278960, 4-86 | US9663506, Example 4-86)
Affinity DataIC50:  9nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM213002(US9278960, 4-86 | US9663506, Example 4-86)
Affinity DataIC50:  9nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM213002(US9278960, 4-86 | US9663506, Example 4-86)
Affinity DataIC50:  9nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent