BDBM213235 FRAX414

SMILES CCn1c2nc(Nc3ccc(cc3)N3CCN(C)CC3)ncc2cc(-c2ccc(Cl)cc2Cl)c1=O

InChI Key InChIKey=IPXXIMKPWSIHQB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 213235   

TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM213235(FRAX414)
Affinity DataIC50:  559nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1 [249-545,K299R](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM213235(FRAX414)
Affinity DataIC50:  20nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed