BDBM2134 1-(4-chloro-1,2-dihydropyridazin-1-yl)-3-[2-(2-cyano-6-fluoro-3-methoxyphenyl)ethyl]thiourea::LY300046HCl Analog 19::N-[2-(2-Cyano-6-fluoro-3-methoxyphenethyl)]-N-[2-(5-chloropyridazyl)]thiourea::PETT deriv.
SMILES COc1ccc(F)c(CCNC(=S)NN2C=CC(Cl)C=N2)c1C#N
InChI Key InChIKey=AMDNSVVNDSKFHO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 2134
Affinity DataIC50: 5nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Eli Lilly
Eli Lilly
Affinity DataIC50: 1.10E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Eli Lilly
Eli Lilly
Affinity DataIC50: 1.10E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair