BDBM213682 US9278981, 274
SMILES O[C@@H]1CCN(C1)c1ncc(cc1-c1cnccc1C#N)C(=O)Nc1ccc(OC(F)(F)Cl)cc1
InChI Key InChIKey=DXIVRSUXKYIPMU-QGZVFWFLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 213682
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Affinity DataIC50: <0.100nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair