BDBM2150 1-(5-chloropyridin-2-yl)-3-[2-(3-cyanofuran-2-yl)ethyl]thiourea::LY300046HCl Analog 36::N-[2-[2-(3-Cyanofuranyl)]ethyl]-N-[2-(5-chloropyridyl)]-thiourea::PETT deriv.

SMILES Clc1ccc(NC(=S)NCCc2occc2C#N)nc1

InChI Key InChIKey=LIYNCRHQGJVEOI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2150   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM2150(1-(5-chloropyridin-2-yl)-3-[2-(3-cyanofuran-2-yl)e...)
Affinity DataIC50:  60nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM2150(1-(5-chloropyridin-2-yl)-3-[2-(3-cyanofuran-2-yl)e...)
Affinity DataIC50:  2.60E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM2150(1-(5-chloropyridin-2-yl)-3-[2-(3-cyanofuran-2-yl)e...)
Affinity DataIC50:  2.60E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed