BDBM21645 (2S)-3-(1H-indol-3-yl)-2-[(2R,3R)-3-phenyl-2-(sulfanylmethyl)butanamido]propanoic acid::Mercaptoacyl amino acid compound, 9b
SMILES C[C@H]([C@@H](CS)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)c1ccccc1
InChI Key InChIKey=NJEGUEXVKDRURH-QMIHWGKISA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 21645
Affinity DataKi: 2.40nM ΔG°: -12.2kcal/molepH: 7.4 T: 2°CAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Specific activity of ACE was assayed in black 96-well microplates with or without various concentrations of inhibitors. N-Cbz-Phe-His-Leu was added, ...More data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:ECE activity was performed in black 96-well microplates with recombinant human ECE-1c (hECE-1c). The hECE-1c was preincubated with or without increa...More data for this Ligand-Target Pair