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BDBM217353 Isoflurane

SMILES: FC(F)OC(Cl)C(F)(F)F

InChI Key: InChIKey=PIWKPBJCKXDKJR-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 217353   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
α7β2 nAChR


(Homo sapiens (Human))
BDBM217353
PNG
(Isoflurane)
Show SMILES FC(F)OC(Cl)C(F)(F)F
Show InChI InChI=1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H
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PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 1.17E+4n/an/an/an/an/a25



University of Pittsburgh



Assay Description
Functional measurements were performed using perforated patch whole cell recordings coupled with a two-barrel drug application system [Liu et al., J....


J Biol Chem 288: 35793-800 (2013)


Article DOI: 10.1074/jbc.M113.508333
BindingDB Entry DOI: 10.7270/Q24748QH
More data for this
Ligand-Target Pair