BDBM2198 (3-(2-tert-Butyl-5-methyl-phenylsulfanyl)-4-hydroxy-6-isopropyl-6-phenethyl-5,6-dihydro-pyran-2-one::3-[(2-tert-butyl-5-methylphenyl)sulfanyl]-4-hydroxy-6-(2-phenylethyl)-6-(propan-2-yl)-5,6-dihydro-2H-pyran-2-one::CHEMBL372040::PD 178390 Analog 37
SMILES CC(C)C1(CCc2ccccc2)CC(=O)C(Sc2cc(C)ccc2C(C)(C)C)C(=O)O1
InChI Key InChIKey=FPODAFKDQIBIAN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 2198
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research
Parke-Davis Pharmaceutical Research
Affinity DataIC50: 1.10nMAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 1.50E+4nMAssay Description:Effective concentration required to inhibit human immunodeficiency virus 1 protease in MT-4 cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against human immunodeficiency virus 1 protease in MT-4 cellsMore data for this Ligand-Target Pair