BDBM22048 9-benzyl-6-{[(2S)-2-methylbutyl]amino}-9H-purine-2-carbonitrile::Compound 3{1,17}

SMILES CC[C@H](C)CNc1nc(nc2n(Cc3ccccc3)cnc12)C#N

InChI Key InChIKey=GNSCEXSWZIAABK-ZDUSSCGKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22048   

TargetCathepsin B-like cysteine protease(Trypanosoma brucei)
University Of California San Francisco

LigandPNGBDBM22048(9-benzyl-6-{[(2S)-2-methylbutyl]amino}-9H-purine-2...)
Affinity DataIC50:  5.00E+3nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed