BDBM221359 US9303023, 55

SMILES COc1ccc(cc1)-c1ocnc1C(=O)Nc1cnn(CCNc2nc(OC)cc(OC)n2)c1

InChI Key InChIKey=AGTYLUDFLBJZNF-UHFFFAOYSA-N

Data  1 IC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221359   

TargetOrexin receptor type 2(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

US Patent
LigandPNGBDBM221359(US9303023, 55)
Show SMILES COc1ccc(cc1)-c1ocnc1C(=O)Nc1cnn(CCNc2nc(OC)cc(OC)n2)c1
Show InChI InChI=1S/C22H23N7O5/c1-31-16-6-4-14(5-7-16)20-19(24-13-34-20)21(30)26-15-11-25-29(12-15)9-8-23-22-27-17(32-2)10-18(28-22)33-3/h4-7,10-13H,8-9H2,1-3H3,(H,26,30)(H,23,27,28)
Affinity DataIC50: 100nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid