BDBM22146 (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[(5-phenyl-1,2,4-thiadiazol-3-yl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::(3R,5S,6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)-2-[(5-phenyl-1,2,4-thiadiazol-3-yl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid::thiadiazole compound, 8a
SMILES CC(C)c1nc(Nc2nsc(n2)-c2ccccc2)nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O
InChI Key InChIKey=MHPTUGAUOGKAGG-DDVDASKDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 22146
Affinity DataIC50: 6.90nM EC50: 7.70nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair