BDBM22160 pyrazole compound, 14a::sodium 5-({5-[(1E,3S,5R)-6-carboxy-3,5-dihydroxyhex-1-en-1-yl]-4-(4-fluorophenyl)-6-(1-methylethyl)pyrimidin-2-yl}amino)-1-methyl-1H-pyrazole-3-carboxylate::sodium 5-({5-[(1E,3S,5R)-6-carboxy-3,5-dihydroxyhex-1-en-1-yl]-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidin-2-yl}amino)-1-methyl-1H-pyrazole-3-carboxylate
SMILES CC(C)c1nc(Nc2cc(nn2C)C(O)=O)nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O
InChI Key InChIKey=FHALQUHVYPUUQM-PIIXRYACSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 22160
Affinity DataIC50: 0.900nM EC50: 13.7nMpH: 7.0 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair