BDBM223087 Phenyl 4-(6-((5-((2-chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)-piperazine-1-carboxylate (3g)
SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cc(nc(C)n2)N2CCN(CC2)C(=O)Oc2ccccc2)s1
InChI Key InChIKey=CHYCQBZNTKXHMV-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 223087
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences
Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences
Affinity DataIC50: 7.14nMpH: 7.5 T: 2°CAssay Description:The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a LanthaScreen Eu kinase activity assay technology (Invitrogen, Carlsbad...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences
Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences
Affinity DataIC50: 0.277nMpH: 7.5 T: 2°CAssay Description:ABL activity assays were performed in 384-well plate using the FRET-based Z'-Lyteassay system and Tyr-2 peptide substrate according to the manufa...More data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences
Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences
Affinity DataIC50: 21.3nMpH: 7.5 T: 2°CAssay Description:The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a LanthaScreen Eu kinase activity assay technology (Invitrogen, Carlsbad...More data for this Ligand-Target Pair