BDBM223979 7-Chloro-N-cyclopentylquinolin-4-amine (1)

SMILES Clc1ccc2c(NC3CCCC3)ccnc2c1

InChI Key InChIKey=ZVSVCLNPECDDKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223979   

TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
Abbvie

LigandPNGBDBM223979(7-Chloro-N-cyclopentylquinolin-4-amine (1))
Affinity DataIC50:  4.80E+3nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase KMT5B(Homo sapiens (Human))
Abbvie

LigandPNGBDBM223979(7-Chloro-N-cyclopentylquinolin-4-amine (1))
Affinity DataIC50:  5.90E+3nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed