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BDBM226898 US9328096, 586

SMILES: Clc1cc(Cl)c(cc1C(=O)Nc1cc(nn1-c1ccccc1)C(=O)NCc1ncccn1)-c1ccccn1

InChI Key: InChIKey=CERUCUMPIOKGHV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226898   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226898
PNG
(US9328096, 586)
Show SMILES Clc1cc(Cl)c(cc1C(=O)Nc1cc(nn1-c1ccccc1)C(=O)NCc1ncccn1)-c1ccccn1
Show InChI InChI=1S/C27H19Cl2N7O2/c28-20-14-21(29)19(13-18(20)22-9-4-5-10-30-22)26(37)34-25-15-23(35-36(25)17-7-2-1-3-8-17)27(38)33-16-24-31-11-6-12-32-24/h1-15H,16H2,(H,33,38)(H,34,37)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 13.6n/an/an/an/an/a37



Pfizer Inc

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


US Patent US9328096 (2016)


BindingDB Entry DOI: 10.7270/Q2FN152J
More data for this
Ligand-Target Pair