BDBM2287 5-chloro-N-methyl-3-(phenylsulfanyl)-1H-indole-2-carboxamide::5Cl3PhS-2IndolCONH2 inhibitor 13

SMILES CNC(=O)c1[nH]c2ccc(Cl)cc2c1Sc1ccccc1

InChI Key InChIKey=BEAHKSVMGOSPPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2287   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2287(5-chloro-N-methyl-3-(phenylsulfanyl)-1H-indole-2-c...)
Affinity DataIC50:  22nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed