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BDBM229602 US9340506, A-1

SMILES: O=C(Nc1nccs1)C(OC1CCOCC1)c1ccc(cc1)S(=O)(=O)C1CC1

InChI Key: InChIKey=BSRQEAFPJLXYDF-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 229602   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucokinase/Glucokinase regulatory protein


(Homo sapiens (Human))
BDBM229602
PNG
(US9340506, A-1)
Show SMILES O=C(Nc1nccs1)C(OC1CCOCC1)c1ccc(cc1)S(=O)(=O)C1CC1
Show InChI InChI=1S/C19H22N2O5S2/c22-18(21-19-20-9-12-27-19)17(26-14-7-10-25-11-8-14)13-1-3-15(4-2-13)28(23,24)16-5-6-16/h1-4,9,12,14,16-17H,5-8,10-11H2,(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.40E+3n/an/a7.2n/a



Advinus Therapeutics Ltd

US Patent


Assay Description
The assay is carried out according to the protocol outlined in Hariharan et al (1997), Diabetes 46: 11-16. Briefly, the test compounds are incubated ...


US Patent US9340506 (2016)


BindingDB Entry DOI: 10.7270/Q2ZG6R3V
More data for this
Ligand-Target Pair