BDBM230231 US9340500, I-075
SMILES Cc1c(cc(C2CCN(CC2)C(=O)OCc2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F
InChI Key InChIKey=DGBAWOXGLXNPSZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 230231
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 130nM ΔG°: -9.77kcal/mole IC50: 270nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair