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BDBM234840 US9353104, 146

SMILES: COc1ccc(nc1)[C@H]1C[C@@H]1COc1cc(NCc2c[nH]nn2)c(=O)n(C)n1

InChI Key:

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234840   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 10A (PDE10A2)


(Homo sapiens (Human))
BDBM234840
PNG
(US9353104, 146)
Show SMILES COc1ccc(nc1)[C@H]1C[C@@H]1COc1cc(NCc2c[nH]nn2)c(=O)n(C)n1
PDB

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
0.0480n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Corp

US Patent


Assay Description
The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...


US Patent US9353104 (2016)


Article DOI: null
BindingDB Entry DOI: 10.7270/Q2ZP4517
More data for this
Ligand-Target Pair