BDBM23500 4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-N-hydroxy-1-(propane-2-sulfonyl)piperidine-4-carboxamide::CHEMBL209970::beta-sulfonyl hydroxamate analogue, 4
SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C(C)C)C(=O)NO
InChI Key InChIKey=CEVLUPQNDFOYSI-UHFFFAOYSA-N
Data 22 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 23500
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research
Wyeth Research
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit the cleavage of the substrate by the purified enzyme in a fluorescence-based fluorescence resonanc...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research
Wyeth Research
Affinity DataIC50: 157nMT: 2°CAssay Description:A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...More data for this Ligand-Target Pair
Affinity DataIC50: 3.64E+3nMT: 2°CAssay Description:A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...More data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
Affinity DataIC50: 4.71E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
Affinity DataIC50: 4.71E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
Affinity DataIC50: 8.78E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research
Wyeth Research
Affinity DataIC50: 1.5nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.78E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research
Wyeth Research
Affinity DataIC50: 1.5nMAssay Description:Inhibition of TACE in human whole blood assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research
Wyeth Research
Affinity DataIC50: 8.78E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
Affinity DataIC50: 280nMpH: 7.4 T: 2°CAssay Description:A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...More data for this Ligand-Target Pair