BDBM23556 3-Carboxamide-coumarin deriv., 32::N-(3-chlorophenyl)-6-methyl-2-oxo-2H-chromene-3-carboxamide

SMILES Cc1ccc2oc(=O)c(cc2c1)C(=O)Nc1cccc(Cl)c1

InChI Key InChIKey=OOLBPPCJUQNAAW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 23556   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM23556(3-Carboxamide-coumarin deriv., 32 | N-(3-chlorophe...)
Affinity DataKi:  1.20nMAssay Description:Noncompetitive inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23556(3-Carboxamide-coumarin deriv., 32 | N-(3-chlorophe...)
Affinity DataAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23556(3-Carboxamide-coumarin deriv., 32 | N-(3-chlorophe...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Porto

Curated by ChEMBL
LigandPNGBDBM23556(3-Carboxamide-coumarin deriv., 32 | N-(3-chlorophe...)
Affinity DataIC50:  5.10nMAssay Description:Noncompetitive inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23556(3-Carboxamide-coumarin deriv., 32 | N-(3-chlorophe...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23556(3-Carboxamide-coumarin deriv., 32 | N-(3-chlorophe...)
Affinity DataIC50:  3.10E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23556(3-Carboxamide-coumarin deriv., 32 | N-(3-chlorophe...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed