BDBM23871 3-[(2S)-3-[4-(4-aminobutanoyl)piperazin-1-yl]-3-oxo-2-{[2,4,6-tris(propan-2-yl)benzene]sulfonamido}propyl]benzene-1-carboximidamide::3-amidinophenylalanine deriv., 15

SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)C(=O)CCCN

InChI Key InChIKey=XIXFFEVKOUVTRE-LJAQVGFWSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23871   

TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Curacyte Chemistry

LigandPNGBDBM23871(3-[(2S)-3-[4-(4-aminobutanoyl)piperazin-1-yl]-3-ox...)
Affinity DataKi:  140nM ΔG°:  -9.34kcal/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Curacyte Chemistry

LigandPNGBDBM23871(3-[(2S)-3-[4-(4-aminobutanoyl)piperazin-1-yl]-3-ox...)
Affinity DataKi:  640nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Curacyte Chemistry

LigandPNGBDBM23871(3-[(2S)-3-[4-(4-aminobutanoyl)piperazin-1-yl]-3-ox...)
Affinity DataKi:  1.10E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Curacyte Chemistry

LigandPNGBDBM23871(3-[(2S)-3-[4-(4-aminobutanoyl)piperazin-1-yl]-3-ox...)
Affinity DataKi:  9.40E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
Curacyte Chemistry

LigandPNGBDBM23871(3-[(2S)-3-[4-(4-aminobutanoyl)piperazin-1-yl]-3-ox...)
Affinity DataKi:  1.30E+4nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed