BDBM239015 US10028934, Compound 4::US10478423, Cpd. 4::US9408850, 4::US9597317, 4

SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(Oc3ccc(OCc4ccccc4)cc3)ccc12

InChI Key InChIKey=GCDURZIHSDVMFZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 239015   

TargetReceptor-type tyrosine-protein kinase FLT3 [564-993](Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239015(US10028934, Compound 4 | US10478423, Cpd. 4 | US94...)
Affinity DataIC50:  974nMpH: 7.9 T: 2°CAssay Description:The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was pre activat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit [544-976](Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239015(US10028934, Compound 4 | US10478423, Cpd. 4 | US94...)
Affinity DataIC50: >1.00E+4nMpH: 7.9Assay Description:The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) was pre ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239015(US10028934, Compound 4 | US10478423, Cpd. 4 | US94...)
Affinity DataIC50:  974nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239015(US10028934, Compound 4 | US10478423, Cpd. 4 | US94...)
Affinity DataIC50: >1.00E+4nMAssay Description:i. Enzyme—The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239015(US10028934, Compound 4 | US10478423, Cpd. 4 | US94...)
Affinity DataIC50:  974nMAssay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239015(US10028934, Compound 4 | US10478423, Cpd. 4 | US94...)
Affinity DataIC50: >1.00E+4nMAssay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239015(US10028934, Compound 4 | US10478423, Cpd. 4 | US94...)
Affinity DataIC50:  974nMAssay Description:i. Enzyme—The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239015(US10028934, Compound 4 | US10478423, Cpd. 4 | US94...)
Affinity DataIC50: >1.00E+4nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent