BDBM239044 US10478423, Ref. Compound::US9408850, Ref. Compound::US9597317, Ref. Compound

SMILES CN(C)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCc3ccccc3)ccc12

InChI Key InChIKey=CQMXHWIVXMYLBS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 239044   

TargetReceptor-type tyrosine-protein kinase FLT3 [564-993](Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239044(US10478423, Ref. Compound | US9408850, Ref. Compou...)
Affinity DataIC50:  3.18E+3nMpH: 7.9 T: 2°CAssay Description:The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was pre activat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit [544-976](Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239044(US10478423, Ref. Compound | US9408850, Ref. Compou...)
Affinity DataIC50: >1.00E+4nMpH: 7.9Assay Description:The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) was pre ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239044(US10478423, Ref. Compound | US9408850, Ref. Compou...)
Affinity DataIC50: >1.00E+4nMAssay Description:i. Enzyme—The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239044(US10478423, Ref. Compound | US9408850, Ref. Compou...)
Affinity DataIC50: >1.00E+4nMAssay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239044(US10478423, Ref. Compound | US9408850, Ref. Compou...)
Affinity DataIC50:  3.18E+3nMAssay Description:i. Enzyme—The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239044(US10478423, Ref. Compound | US9408850, Ref. Compou...)
Affinity DataIC50:  3.18E+3nMAssay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent