BDBM23929 1,3-dichloro-5-[(E)-2-(4-chlorophenyl)ethenyl]benzene::trans-Stilbene Derivative, 4b
SMILES Clc1ccc(\C=C\c2cc(Cl)cc(Cl)c2)cc1
InChI Key InChIKey=JMYNPQVCVQVODQ-OWOJBTEDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 23929
Affinity DataKi: 1.20nM ΔG°: -11.3kcal/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Cytosols from MCF-7 cells expressed ER-alpha isoform were incubated with [3H]-estradiol and eight concentrations of unlabeled test ligands. IC50 val...More data for this Ligand-Target Pair
Affinity DataKi: 8.32E+8nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 8.34E+8nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hyogo University Of Health Sciences
Curated by ChEMBL
Hyogo University Of Health Sciences
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as induction of calcium influx at 30 uM after 6 mins by Fluo-4 dye-based assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hyogo University Of Health Sciences
Curated by ChEMBL
Hyogo University Of Health Sciences
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human TRPA1 expressed in HEK293 cells assessed as decrease in AITC-induced calcium influx preincubated for 6 mins followed by AITC addi...More data for this Ligand-Target Pair