BDBM23942 1,3-difluoro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]benzene::cis-Stilbene Derivative, 5c

SMILES COc1ccc(\C=C/c2cc(F)cc(F)c2)cc1

InChI Key InChIKey=JXXRRHGSTQRHIL-IHWYPQMZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23942   

TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23942(1,3-difluoro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...)
Affinity DataKi:  22nM ΔG°:  -9.70kcal/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Institut Claudius Regaud

LigandPNGBDBM23942(1,3-difluoro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...)
Affinity DataKi: >1.00E+5nMAssay Description:Cytosols from MCF-7 cells expressed ER-alpha isoform were incubated with [3H]-estradiol and eight concentrations of unlabeled test ligands. IC50 val...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23942(1,3-difluoro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...)
Affinity DataKi:  4.55E+7nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article