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BDBM239562 US9394309, 15

SMILES: Cc1ccc(NC(=O)c2cccc(c2)S(F)(F)(F)(F)F)cc1-n1ccn2nc(cc12)-c1cccnc1

InChI Key: InChIKey=GZIAFFUATWCMSP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 239562   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase receptor TIE-2


(Homo sapiens (Human))
BDBM239562
PNG
(US9394309, 15)
Show SMILES Cc1ccc(NC(=O)c2cccc(c2)S(F)(F)(F)(F)F)cc1-n1ccn2nc(cc12)-c1cccnc1
Show InChI InChI=1S/C24H18F5N5OS/c1-16-7-8-19(31-24(35)17-4-2-6-20(12-17)36(25,26,27,28)29)13-22(16)33-10-11-34-23(33)14-21(32-34)18-5-3-9-30-15-18/h2-15H,1H3,(H,31,35)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 24n/an/an/an/a7.022



Bayer Pharma Aktiengesellschaft

US Patent


Assay Description
For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...


US Patent US9394309 (2016)


BindingDB Entry DOI: 10.7270/Q2C53JRC
More data for this
Ligand-Target Pair