BDBM239563 US9394309, 16

SMILES Cc1nccn1-c1cc(cc(c1)S(F)(F)(F)(F)F)C(=O)Nc1ccc(C)c(c1)-n1ccn2nc(cc12)-c1cccnc1

InChI Key InChIKey=GACVWXAKDOTVRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239563   

TargetAngiopoietin-1 receptor [776-1124](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM239563(US9394309, 16)
Affinity DataIC50:  3.20nMpH: 9.6 T: 2°CAssay Description:For measuring the autophosphorylation of the endogenous Tie2 receptor in the cell lysates prepared, a self-prepared anti-Tie2 antibody directed again...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAngiopoietin-1 receptor [776-1124](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM239563(US9394309, 16)
Affinity DataIC50:  0.700nMpH: 7.0 T: 2°CAssay Description:For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent