BindingDB logo
myBDB logout

BDBM239634 US9394309, 87

SMILES: FS(F)(F)(F)(F)c1cc(cc(c1)C(=O)Nc1cccc(c1)-n1ccn2nc(cc12)-c1cccnc1)C#N

InChI Key: InChIKey=YZHGBZUWBYLZAC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 239634   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase receptor TIE-2


(Homo sapiens (Human))
BDBM239634
PNG
(US9394309, 87)
Show SMILES FS(F)(F)(F)(F)c1cc(cc(c1)C(=O)Nc1cccc(c1)-n1ccn2nc(cc12)-c1cccnc1)C#N
Show InChI InChI=1S/C24H15F5N6OS/c25-37(26,27,28,29)21-10-16(14-30)9-18(11-21)24(36)32-19-4-1-5-20(12-19)34-7-8-35-23(34)13-22(33-35)17-3-2-6-31-15-17/h1-13,15H,(H,32,36)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 980n/an/an/an/a7.022



Bayer Pharma Aktiengesellschaft

US Patent


Assay Description
For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...


US Patent US9394309 (2016)


BindingDB Entry DOI: 10.7270/Q2C53JRC
More data for this
Ligand-Target Pair